LCZ696(沙库必曲)杂质列表_标准品|对照品|国产杂质|杂质定制-上海启太生物科技有限公司

LCZ696(沙库必曲)杂质列表
2017-08-31 18:17

中文名称: LCZ696、沙库必曲-缬沙坦

英文名称: Sacubitril

CAS号: 1426129-50-1

商品名：entresto

适应症：entresto是结合sacubitril，一脑啡肽酶抑制剂，和缬沙坦，血管紧张素Ⅱ受体阻断剂，以减少风险心力衰竭患者的心血管死亡及住院治疗慢性心力衰竭（NYHAII-IV级）和射血分数降低

LCZ696(沙库必曲)杂质列表（Sacubitrile Impurity)-上海启太生物
序号	产品名	英文名	结构式	CAS号	分子量
1	LCZ696杂质A (2S,4R)-AHU377 534-06	Sacubitril Impurity A		761373-05-1	C24H29NO5 411.50
2	LCZ696杂质B (2R,4R)-AHU377 536-06	Sacubitril Impurity B		766480-48-2	C24H29NO5 411.50
3	LCZ696杂质C (2S,4S)-AHU377 535-06	Sacubitril Impurity C		149709-63-7	C24H29NO5 411.50
4	LCZ696杂质D (2S,4R)-AHU08 696-A-c	Sacubitril Impurity D		1012341-54-6	C23H29NO4 383.49
5	LCZ696杂质E (2R,4R)-AHU08 696-A-b	Sacubitril Impurity E		1012341-56-8	C23H29NO4 383.49
6	LCZ696杂质F (2S,4S)-AHU08 696-A-a	Sacubitril Impurity F		1012341-52-4	C23H29NO4 383.49
7	LCZ696杂质G (2R,4R)-AHU09	Sacubitril Impurity G		NA	C20H26ClNO2 347.88
8	LCZ696杂质H (2S,4S)-AHU09	Sacubitril Impurity H		753421-85-1	C20H26ClNO2 347.88
9	LCZ696杂质I (2S,4R)-AHU09	Sacubitril Impurity I		NA	C20H26ClNO2 347.88
10	LCZ696杂质J AHU06a	Sacubitril Impurity J		NA	C25H31NO4 409.53
11	LCZ696杂质K AHU07a	Sacubitril Impurity K		NA	C23H27NO4 381.47
12	LCZ696杂质L BOA04a	Sacubitril Impurity L		NA	C20H25NO3 327.42
13	LCZ696杂质M AHU02a	Sacubitril Impurity M		NA	C21H25NO4 355.43
14	LCZ696杂质N BOA03a	Sacubitril Impurity N		NA	C15H17NO 227.31
15	LCZ696杂质O 900-04	Sacubitril Impurity O		149709-62-6	C22H25NO5 383.44
16	LCZ696杂质P 547-06 (2R,4S)-AHU08	Sacubitril Impurity P		1012341-50-2	C23H29NO4 383.48
17	LCZ696杂质Q 548-06	Sacubitril Impurity Q		149690-12-0	C20H26ClNO2 347.88
18	LCZ696杂质R 506-07	Sacubitril Impurity R		NA	C22H23NO4 365.42
19	LCZ696杂质S 537-06	Sacubitril Impurity S		1038924-70-7	C18H19NO 265.35
20	LCZ696杂质T 516-07	Sacubitril Impurity T		NA	C27H35NO5 453.57
21	LCZ696杂质U 550-06	Sacubitril Impurity U		1038924-97-8	C24H27NO4 393.48
22	LCZ696杂质V 575-11	Sacubitril Impurity V		1038924-71-8	C18H22ClNO2 319.83
23	LCZ696杂质W 576-11	Sacubitril Impurity W		149709-60-4	C25H33NO4 411.53
24	LCZ696杂质X 504-09	Sacubitril Impurity X		NA	C50H60N2O10Ca 889.10
25	LCZ696杂质Y 004-08	Sacubitril Impurity Y		NA	C26H33NO5 439.54
26	LCZ696杂质Z 518-12	Sacubitril Impurity Z		1639970-62-9	C22H23NO4 365.42
27	LCZ696杂质1 519-12	Sacubitril Impurity 1		NA	C25H29NO4 407.50
28	LCZ696杂质2 520-12	Sacubitril Impurity 2		NA	C25H29NO4 407.50
29	LCZ696杂质3 521-12	Sacubitril Impurity 3		NA	C25H31NO5 425.52
30	LCZ696杂质4 531-12	Sacubitril Impurity 4		NA	C46H52N2O10Ca 832.99